By: Rani Helvey-Byers, PT, DPT, OCS
When it comes to exercise, the way you train matters as much as what you train. The same movement — be it a squat or a row — can achieve different results depending on the sets, reps, load, and the length of the rest breaks you use.
Understanding these variables helps you train smarter and get better results, whether you’re working to recover from an injury, build muscle, or simply move better through life.
Below, we’ve broken down exactly how to target your exercises to your goals, be it to improve muscle activation, endurance, strength or power.
Muscle Activation (Neuromuscular Re‐education)
Goal: Reconnect your brain and body — ideal early in rehab or when retraining proper movement patterns.
How:
Reps: ~8-15 slow, controlled repetitions
Sets: ~1-2
Rest: ~30-60 seconds between sets
Load: Light to moderate resistance — focus on form and muscle engagement
Example: Glute bridges or clamshells to re-awaken the hip muscles after injury
Tip: Think “quality over quantity.” Make sure to feel the right muscle working, not just moving through the motion.
Muscle Endurance
Goal: Improve a muscle’s ability to work for longer periods — great for endurance athletes, improving posture, daily activities, and joint stability.
How:
Reps: ~12-20 (sometimes even 25 for smaller muscles)
Sets: ~2-3
Rest: ~30-60 seconds
Load: Light to moderate resistance that causes fatigue near end of set
Example: Shoulder external rotations or wall sits to build endurance in stabilizing muscles
Muscle Strength
Goal: Build the ability to produce force — helpful for injury prevention, building stronger athletes, affecting bone density, and preventing falls
How:
Reps: ~6-10
Sets: ~3-4
Rest: ~1-3 minutes between sets
Load: Moderate to heavy resistance (challenging yet safe)
Example: Squats, rows, or deadlifts performed with good control
Research note: The ACSM recommends starting at ~8-12 repetitions for those who are new to exercise. They provide a broader suggestion of 1-12 reps for more advanced exercisers.
Muscle Power
Goal: Generate force quickly — essential for athletes as well as older adults working to improve balance and prevent falls.
How:
Reps: ~3-6 (explosive effort on each rep)
Sets: ~3-5
Rest: ~2-3 minutes between sets
Load: Light to moderate resistance, moved fast and controlled
Example: Medicine-ball throws, jump squats, or quick step-ups
💡 Putting It All Together
Your ideal rep/set/rest range depends on your current ability and your goals. Many people benefit from cycling through phases — focusing first on activation, then endurance, then strength, and finally power as movement quality and confidence improve.
If you’re not sure where to start, your physical therapist can help you build a personalized progression that keeps you safe, strong, and steadily improving.
Bottom line:
You don’t have to overhaul your workouts — just fine-tune the details. The right sets, reps, rest and load can transform an ordinary exercise into a powerful tool for your goals.

Click Here to schedule your next appointment with the experts at MEND

