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Understanding Unilateral Temporomandibular Joint (TMJ) Pain: Causes and Conservative Treatment

October 20, 2025

By: John Crawley, PT, DPT, OCS

The nature of TMJ related pain can be complex. Often manifesting from a combination of bio mechanical and behavioral factors. Based on a synthesis of peer-reviewed research and systematic reviews, the top five contributing factors or management components for TMD-related pain are:

  1. Muscle Disorders (Myofascial Pain): This is one of the most common causes of TMD and unilateral pain, characterized by pain in the muscles of mastication (chewing) and potentially referred pain to other areas of the head and neck.
  2. Intra-articular Disorders (Disk Displacement): Derangement of the articular disk within the TMJ, with or without reduction, can cause joint pain, clicking, and limited mouth opening.
  3. Parafunctional Habits/Oral Behaviors (OBs): Common daily habits such as teeth clenching (bruxism), muscle tensing, and excessive gum chewing can create microtrauma and muscle overuse, significantly contributing to pain. 
  4. Cervical Spine Dysfunction: Pain or dysfunction in the neck region is often co-present and can refer pain to the temporomandibular region. 
  5. Psychosocial Factors: Conditions like chronic stress, anxiety, depression, and poor sleep quality are frequently linked with chronic TMD.

A comprehensive, multidisciplinary approach that is both conservative and reversible is the gold standard for initial management. Physical therapy, which includes manual therapy and therapeutic exercises (TE), has been consistently supported in peer-reviewed literature for its effectiveness in reducing pain and improving maximum mouth opening (MMO). Specifically, the combination of manual therapy on the TMJ/cervical region and therapeutic exercise appears to be crucial for the long-term maintenance of desirable effects on pain and mouth opening. Furthermore, patient education and self-management strategies—such as eating a soft food diet, practicing good sleep hygiene, and actively avoiding harmful oral behaviors—are considered a necessary first step that empowers the patient and supports the long-term success of other physical interventions.

  1. Manual Therapy (MT):
  • Description: Hands-on techniques applied by the therapist to the temporomandibular joint (TMJ), masticatory muscles, and often the cervical spine. This includes joint mobilization where the jaw is moved by the therapist in a variety of ways to improve jaw range of motion and soft-tissue techniques (e.g., myofascial release, dry-needling, or trigger point therapy) to reduce muscle tension and pain.
  1. Therapeutic Exercise (TE):
  • Description: Active programs focused on restoring normal jaw function, muscle strength, and coordination. Exercises typically include stretching, isometrics (for muscle strengthening), and coordination exercises (to guide the jaw into a proper, pain-free opening and closing pattern).
  1. Patient Education and Self-Care:
  • Description: Educating the patient on the causes of TMD and teaching self-management techniques. Key components include:
    • Resting Jaw Position: Keeping the teeth slightly apart, with the tongue on the roof of the mouth.
    • Diet Modification: Avoiding hard, chewy, or crunchy foods.
    • Habit Modification: Avoiding clenching, chewing gum, or leaning on the jaw
    • Etiology and prognosis: Informing the patient about the time course of the problem and what factors are contributing to their jaw pain. 

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 References 

  1. Herrera-Valencia V, Ruiz-Muñoz M, Argüelles-Valencia A, et al. Efficacy of Manual Therapy in Temporomandibular Joint Disorders and Its Medium-and Long-Term Effects on Pain and Maximum Mouth Opening: A Systematic Review and Meta-Analysis. J Clin Med. 2020;9(11):3404.
  2. Armijo-Olivo S, Pitance L, Singh V, Neto F, Thie N, Michelotti A. Effectiveness of manual therapy and therapeutic exercise for temporomandibular disorders: systematic review and meta-analysis. Phys Ther. 2016;96(1):9-25.
  3. Gębska M, Gębski A, Nitecka-Buchta A, Czuba K. Evaluation of the efficacy of manual soft tissue therapy and therapeutic exercises in patients with pain and limited mobility TMJ: a randomized control trial (RCT). Head Face Med. 2023;19(1):42.
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